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New Naprosyn EC 500 Mg 20 Tablets ingredient Naproxen Sodium View larger

Naprosyn EC 500 Mg 20 Tablets ingredient Naproxen Sodium

NPR2564

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Active ingredient
An enteric tablet contains 500 mg of naproxen.

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Things to consider before using NAPROSYN Do not use NAPROSYN CR in the

following situations

Cardiovascular system risks

- NAPROSYN CR may cause fatal, thrombotic (coagulation-related) events, an increased risk of heart attack and stroke. This risk may increase depending on the duration of use. The risk may be higher in patients with cardiovascular disease or those with cardiovascular disease risk factors.

- NAPROSYN CR should not be used to treat pain prior to coronary artery etkil bypass m surgery

Risks related to the digestive system

- NSAIDs cause serious undesirable effects that may be fatal, such as bleeding, wound formation, gastric or intestinal perforation. Elderly patients are at increased risk for these serious

If you are

illnesses •allergic to NAPROSYN CR's components, medicines that contain naproxen or naproxen sodium, or if you are suffering from aspirin or other pain, fever, or inflammation. effective drugs asthma syndrome in you, do not use if it generates inflammation in colds and nasal

cavity.'veused before pain, fever and one of inflammation effective drugs have caused to you in the gastro-intestinal bleeding or destruction or still active or if you have recurrent gastric and duodenal ulcers, two or more times , tnot use if you have

• Dosevere kidney, liver or heart failure.

• Do not use before and after coronary artery bypass surgery.

• Do not use if the patient is under 16 years of age.

• Do not use if you are breastfeeding or if you are in the last 3 months of your pregnancy.

CAREFULLY USE NAPROSYN CR in the following cases

• Avoid using with any of the group of medications effective for pain, fever and inflammation.

By using the lowest dose, you can minimize the undesirable effects, as soon as necessary to ensure treatment.

• If you have a previous serious gastrointestinal disorder or symptoms, bleeding, ulcers or damage may develop at any time during treatment. Most of the serious gastrointestinal disorders associated with pain, fever and inflammation have emerged in elderly and disabled patients. For this reason, if you have severe gastrointestinal discomfort such as ulcers, bleeding and damage, your doctor will advise you to start treatment with the lowest dose and use some protective drugs (such as misoprostol or proton pump inhibitors). You should also take a protective medication if you need to use low-dose aspirin or other medicines that may cause gastrointestinal bleeding.

If you have an inflammatory bowel disease (ulcerative colitis, Crohn's disease), you can increase the severity of your discomfort, pain, fever and inflammation drugs, use caution. If you have had gastrointestinal poisoning before, report to your doctor any signs of abdominal discomfort. Do not continue to use NAPROSYN CR in case of gastrointestinal bleeding or ulceration.

If you have stomach bowel disease, use NAPROSYN CR at the doctor's control.

As with other pain, fever and inflammation drugs, the incidence and severity of gastrointestinal disorders may increase with the increase in NAPROSYN CR dose and duration of treatment.

Care should be taken when using oral contraceptives, drugs that prevent blood clotting such as warfarin, ulceration such as aspirin, or medications that can increase the risk of bleeding.

Elderly patients should use NAPROSYN CR at the lowest dose in order to increase the incidence of severe gastrointestinal bleeding and damage.

• Do not continue to use NAPROSYN CR in cases of exfoliation, mucosal damage or hypersensitivity to the skin.

Allergy to the face and throat swelling, bronchus narrowing (asthma) and cold use such as hypersensitivity use with caution. In patients with asthma or allergic disease or aspirin susceptibility, spasm formation may be accelerated in bronchi.

As with other pain, fever and drugs that are effective on inflammation, NAPROSYN CR should be used with caution in patients with kidney disease. Be careful if you have a discomfort in your blood volume or kidney blood flow, heart failure, impaired liver function. Your doctor will reduce the NAPROSYN CR dose you use.

As with other pain, fever and inflammation-effective drugs, NAPROSYN CRliver

may cause elevations in yourfunction test.liver

Caution should be exercised against signs and symptoms showing impairedfunction (nausea, fatigue, drowsiness, itching, jaundice, pain in the upper right of the abdomen, flu-like symptoms). Care should be taken against severe liver disorders, including jaundice and hepatitis.

Naproxen, in your blood, clotting involved in the blood clotting involved in reducing the time of hemorrhage prolongs the time of bleeding, if you are under the control of the doctor continue NAPROSYN CR treatment. When using NAPROSYN CR, there may be an increased risk of bleeding if you have a high risk of bleeding or if you use a medication that prevents blood clotting.

If you experience visual impairment when using NAPROSYN CR, have an eye examination.

Be careful when using NAPROSYN CR if you have a high blood pressure problem or heart failure due to the risk of fluid retention and edema caused by drugs effective from pain, fever and inflammation.

If you have uncontrolled high blood pressure, heart failure due to heart failure, edema, liver disease if you have a significant disease, if you have a disease due to insufficient blood supply, please inform your doctor. Your doctor will consider these conditions during your treatment with NAPROSYN CR.

If you have a high risk of cardiovascular disease (high blood pressure, diabetes, smoking) your doctor will consider these conditions for your long-term treatment with NAPROSYN CR.

As with other pain, fever, and inflammatory drugs, NAPROSYN CR can cause serious side effects, such as heart attacks or stroke, which can result in death or death in a hospital.

Although the events related to the serious cardiovascular system may occur without any stimulus symptoms, contact your doctor if symptoms such as chest pain, shortness of breath, weakness, difficulty in speech are observed.

• Caution should be used with caution in those at risk of Alzheimer's disease (disease characterized by forgetfulness).

4,Please consult with your doctor if theseare valid for you, even at any time in the past. In

stimuliUsingfood and drink

NAPROSYN CR withDo not take meals with meals as NAPROSYN interacts with CR.

Pregnancy

Consult your doctor or pharmacist before using the medicine.

It requires a good evaluation of the benefits and the risks it will bring to the patient. Therefore, the drug should not be used during pregnancy unless it is very necessary. It should not be used in the last 3 months of pregnancy.

If you discover that you are pregnant during treatment, consult your doctor or pharmacist immediately.

Breastfeeding

Consult your doctor or pharmacist before using the medicine.

Naproxen should not be given to breastfeeding mothers.

Tools and machinesuse

CarNaprosynuse in some patients with dizziness, vertigo, insomnia or depression may form. If you have these and other undesirable effects, be careful when performing activities that require attention

important information about some of the excipients

NAPROSYN CR containsNAPROSYN CR contains 0.64 mg of sunset yellow in one tablet. May cause allergic reactions.

Use with other medicines

If you take with the acid-regulating drugs or cholesterol, the effect of NAPROSYN CR may be delayed.

Taken together with meals may cause a decrease in effect.

Napsoxene binds to a protein in the blood called albumin. Your doctor will adjust the dose of NAPROSYN CR because the coumarin type may interfere with anticoagulant drugs, sulfonylureas, hydantoins, other pain, fever and inflammation (NSAID) drugs, and other drugs that bind to albumin, such as aspirin.

Naproxen may delay clotting, called platelets, by reducing the activity of cells involved in blood clotting.

Caution should be exercised in combination with probenecid (a drug that improves urinary excretion of uric acid), as naproxen may cause a higher efficacy in a shorter time.

Be careful when you use it with methotrexate (a drug used to treat cancer). Naproxen may reduce the excretion of methotrexate and cause side effects of methotrexate.

Caution should be exercised as it may cause harmful effects on the kidneys if used together with cyclosporins (a drug that suppresses the immune system).

Do not use naproxen for 8-12 days after using mifepristone because naproxen will decrease the effect of mifepristone (low drug).

Use with aspirin and NAPROSYN CR, such as aspirin, NSAIDs, is not recommended due to an increase in the potential for adverse events.

It can reduce the effect of beta blockers used for high blood pressure treatment. Naproxen and other pain, fever and inflammation drugs can reduce the effect of drugs used to treat high blood pressure and increase the risk of kidney damage of the ACE inhibitor.

Combination of diuretic drugs, such as furosemide, with pain relievers and anti-inflammatory drugs, may increase the risk of developing renal failure.

When used in combination with lithium (used in mental disorders), lithium blood levels may increase and side effects may occur.

In combination with tacrolimus, drugs effective for pain, fever and inflammation may increase the risk of kidney damage.

When used in combination with Cyclosporine and Tacrolimus, an immunosuppressive drug, the risk of kidney damage may increase.

When drugs used to relieve pain, fever and inflammation are used in conjunction with glycosides which increase the contraction power of the heart, it can increase the concentration of blood by increasing the cardiac failure.

The drugs that are effective in treating pain, fever, and inflammation in which Naprosyn is present can increase the risk of blood diseases when used in combination with Zidavudine, which is effective in retroviruses, including human immunodeficiency virus (H1V).

When used together with SSRIs used to treat pain, fever and inflammation, and the treatment of depression, the risk of bleeding of digestive system increases.

As with other pain, fever and inflammation drugs, when used with steroids, the risk of digestive system ulcers and bleeding increases.

In animal studies, when pain, fever and inflammation-effective drugs and quinolone group antibiotics are used together, the risk of severe rhythmic contraction (convulsions) may increase in all or some of the voluntary muscles.

NAPROSYN CR and co-administration of pain, fever and inflammation drugs are not recommended.

As with other pain, fever and inflammatory drugs, caution should be exercised due to the risk of ulcers and bleeding in the gastrointestinal tract when administered with contraceptives.

Please note that these expressions may also apply to products that have been used for some time or that will be used for some time in the future.

Please inform your doctor or pharmacist if you are currently using any prescription or non-prescription medication or if you have recently used it.



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